악골결손 재건을 위한 탈회 및 비탈회 동결건조 동종골의 이용
Use of dimineralized and mineralized freeze-dried allogenic bone graft for the correction of maxillofacial derformities : case reports
소속 상세정보
이기혁
여환호/김영균/김수관/이병준/박인순/엄인웅
KMID : 0360119960180030371
Abstract
Bone graft has been used to repair one defect caused by disease and trauma, congenital and acquired deformities. Graft materials are autogenous bone, allogenic bone, xenogenic bone, synthetics. Autogenous bone graft is the most superior to other
materials for immunologic reaction, compatibility to host tissue, and revascularization. However, autogenous bone graft is required for additional operation and the amount of taking is limited. Autografts are obtained at own expense and also
limited in
size, shape. In order to compensate these problems, allogenic bone graft has been used increasingly. But allogenic bone graft encounters immunologic complications. Therefore, it has been used after freezing, lyophilization or demineralization.
Allogenic
bone processed by only lyophilization includes potential antigenic properties on its surface, therefore it is demineralized to deplete immunologic reaction. Demineralized bone releases BMP and helps the mesenchymal cells tranform to the
chondroblast to
produce cartilage and bone. This reaction is called osteoinducation. Many authors have reported that mineralized lyophilized bone had less antigenicity clinically and favorable bony consideration with host bone.
In our department from 1995 to now, we have used banked allogenic bone graft that has been prepared from Wonkwang Bone Bank in 5 cases and mineralized lyophilized bone graft in 2 cases to reconstruct the maxillofacial bone defect after tumor
resection
and cyst enucleation and cleft alveolus. We will report with literature review that the result is favorable functionally and esthetically.
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